The profoundly different degrees of bioavailability between K1 and K2 is due to their differences in structure only 10-20% of vitamin K1 that is absorbed from food even reaches the circulation, while the long side-chain of vitamin K2 allows it to bind with fat particles in circulation and facilitate its arrival at soft tissue, bones and arteries. In addition, though both reach the liver, most of the K1 is used for purposes of coagulation, with little left over to support the body’s needs elsewhere. Numerous studies have shown that vitamin K2 is the more bioavailable form of the nutrient, and more powerfully influences bone building than K1. Vitamin K occurs in 2 main forms: K1 (phylloquinone), derived from foods such as green leafy vegetables and K2 (menaquinone), which is a group of related compounds differentiated by their side chains. While vitamin D has long been known to assist calcium absorption, it is vitamin K, through its carboxylation of osteocalcin, which guides this calcium to bones and prevents their absorption into organs, joint spaces and arteries.
MCTs are a great way to deliver pure, tasteless and odorless liquid vitamin K2 and D3 that combine easily with any beverage. Natural medium-chain triglycerides have unique physical properties that allow them to be readily absorbed without additional emulsifying agents.
Liquid Vitamin D3 with K2 utilizes a medium chain triglyceride (MCT) delivery system providing 10 mcg of MenaQ7® PRO, the most widely studied form of vitamin K2 as MK-7, and 1,000 IU of vitamin D3 per serving. Thus, vitamin K and vitamin D not only share similar qualities but they also act synergistically with one another within the body. Vitamin K also provides critical cardiovascular protection by helping to activate matrix Gla protein (MGP), an inhibitor of circulatory calcification. In addition, vitamin K has been found to help maintain bone mineral density by decreasing the activity of osteoclasts, a cell that breaks down the bone matrix.
Through its activation of the protein osteocalcin, vitamin K helps to bind newly absorbed calcium to the mineral matrix in bone. A group of naturally occurring and structurally similar, fat-soluble vitamins, vitamin K is essential for the proper utilization of calcium. New research is focusing on the synergistic relationship between vitamin K2 and vitamin D3, for bone and cardiovascular health.
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